Although this mutation is fairly uncommon, however if you do have this mutation it can significantly impact many areas of your health.
I have found that there is a great misconception by many, including doctors, about the concept of senescence. Most believe it is just simply ‘old age’, but its far more....
Since our physiology is not static and things such as enzyme levels and trace mineral are in a constant state of flux, not to mention genetic variances, all which affect metabolization, combined with the fact that the FQ molecule is very complex, there is no way of determining if the same decomposed and identifiable compound will form an adduct in each person.
In this knee jerk reaction the FDA ruling makes the assumption that "We the People" are not responsible enough or smart enough to own or understand our own genetic information.
Just learning if adductions exist or not is not the end, just the opposite, it would open up a vast array of questions, resulting in the need for far more research. If you are looking with an unbiased filter you will see a highly heterogeneous mix of results.There may end up being one cause, but there definitely is not one destination.
The GSTP1 are a family of enzymes that play an important role in detoxification of certain products.
The COMT V158M +/+ polymorphism is associated with improved cognition, better memory and attention to tasks due to higher amounts of dopamine in the synapses.