Magnesium plays a role in many processes throughout the human body. Mg acts as a as a “co-factor” and/or “activator” in many chemical reactions. We need magnesium to produce ATP, and in the construction and regulation of DNA, RNA, and proteins. Magnesium also acts on nerves and muscles, plays a role in insulin-mediated glucose movement into cells, and inﬂuences metabolism. It can aﬀect our heart rhythm and blood pressure, as well as boost bone health by increasing calcium absorption [1, 2, 3].
There are several genes that are related to the processing and handling of Mg in the human body. Many people have variations in these genes which can cause decreased magnesium levels. In the past, one theory that has been proposed for the probability of an increased chance of an adverse event to the fluoroquinolones is having the SNP’s that would code for lower levels of intracellular magnesium. Unfortunately, as of the writing of this article, most doctors do not adequately investigate magnesium before prescribing fluoroquinolones.
For more information on Magnesium in general this SelfHacked page has great information written by Biljana Novkovic PhD.