Dr. Charles Bennett is a tireless advocate for the fluoroquinolone community.  His group SONAR (The Southern Network on Adverse Reaction project) based out of Dr Bennettthe University of South Carolina School of Medicine provides a systematic approach to pharmacovigilance and drug safety. Wherever necessary, SONAR seeks to make global policy changes that reflect the true dangers that certain drugs could pose to the general public.

Over the years as part of his ongoing work into adverse drug events and reactions, Dr. Bennett and SONAR, have researched and synthesized a tremendous amount of existing data regarding the fluoroquinolones (FQ’s).  During that time, our small floxed group has worked closely with Dr. Bennett and SONAR to help facilitate their goals regarding drug safety of the FQ’s.  Recently, in July 2018,  Dr. Bennett published a paper about Fluoroquinolone Associated Suicide to the European Journal of Internal Medicine with the assistance of the floxed community.

Suicide is a huge global health problem and is the tenth leading cause of death in the United States. Several case reports have raised concerns that exposure to fluoroquinolones (FQs) may increase the risk of suicidal behavior. Though FQs, including levofloxacin, ciprofloxacin, and moxifloxacin have been available for the last 3 decades, there has been a significant paradigm shift about their safety in the last five years.

This work was funded partly by the National Institutes of Health (Grant No. R01CA16509), the American Cancer Society (IRG-13-043- 01), Supporting Outstanding Academic Research Seed Grants at USC (SOAR-USC), the South Carolina Smart State Program, and unrestricted grants from Doris Levkoff Meddin and Frank P and Josie M Fletcher to the Center for Medication Safety and Efficacy of the Medical University of South Carolina and the University of South Carolina. No funds were accepted from a pharmaceutical manufacturer or a pharmaceutical distributor. The authors wish to acknowledge the contributions of Travis Bailey, Robert C Kane, MD, Andrew C. Bennett, Carolyn Banister PhD, and from the FQ community, Linda Martin, Alan Redd, David Melvin, Terry Ashton, John Fratti and Jennifer Wilcox to the manuscript preparation.  The late Raja Fayad also contributed to the manuscript preparation.

You can read Doctor Bennett’s paper here.  Hosted with permission.

Please stay tuned to MyQuinStory for updated reports on this and other FQ’s related news.