The following article contains content that certain audiences my find disturbing.
The following is a lengthy article from Dr. Jack Kruse on Fluoroquinolone (FQ’s) Toxicity. Dr. Kruse’s ideas on the mechanisms of FQ Toxicity were published on April 6, 2016 (1). Dr. Kruse’s ideas are complex for the average reader, but I believe there is some insightful information that can be gleaned from it. This, for me, has been confirmed from successes of varying levels, reported to me from floxed folks that have used some of these techniques, both intentionally and inadvertent, over the years. Again these are not universal by any means, nor do I agree with everything Dr. Hack Kruse writes about, but it can give some folks ideas to research, especially sun light as therapy.
One of the more important things is that you must understand how Cipro inflicts its damage. The drug, like many drugs now used in medicine, contains halogens which act as dielectric blockers
for water. The reason for this is that low molecular weight halogens are very electronegative and they love to capture electrons. A loss of electrons from collagen to halogens is a big problem. Why is that? Well, electrons are excited by light released from collagen when it in a cell. When collagen its helical structure due to a loss of electrons it loses its structural ability and its ability to carry energy using piezoelectricity. In technology who use silicon semiconductors, electron loss can also happen due to something called “gate leakage”.
Now here is where the story of biologic semiconduction gets interesting. Biologic gates are designed not to be leaky. Technology uses blue light and nnEMF which make our biologic semiconductors leaky by destroying the dielectric constant in cell water.
Brownian Motion
Brownian motion was discovered in 1827 in plants. What does it mean? = statistical motions of atoms. This implied that the second law of thermodynamics was not an absolute, but a statistical law. Maxwell proved this mathematically in 1867 and then came up with a term called Maxwell demon to describe its ability. In essence what the math described was a rectifying current in a modern semiconductor. So how did we go from atomic plant motions under a scope to Intel? Einstein realized 38 years later this the demon Maxwell was talking about in 1867 could actually be seen in the world. You just had to know where to look for it. Do you know, of Einstein’s 4 miracle papers of 1905 that the one on the Brownian motion is the one most cited? Yet, he won no prizes for it.
Maxwell was the first to show that the second law of thermodynamics had to be statistical. Einstein showed Brownian motion was the observation of the statistical event predicted by Maxwell. In the 1950’s science really upped this game when transistors and semiconductors were found. Why? Any trap door that opens in one direction only and requires a specific amount of energy to open it is essentially a Maxwell Demon. This idea alone is what gave birth to solid state devices we use today in all tech gadgets. What are they and how do they relate or disconnect cells from their life force?
Rectifiers let current pass in one direction and not in reverse, thereby converting AC currents to DC ones. In the 1960’s Dr. Robert O. Becker showed bone had a rectifying current built by light from the sun in the periosteum. Most MD’s still don’t know he did this that long ago. Shameful. The implication of these “light and electric gates” is that these semiconducting gates can randomly convert a fluctuating current of electrons in a membrane into a DC current that can be used for physiologic work. When we eat food and go out sometimes or remain connected to the Earth here and there we develop an alternating current in our cell membranes and mitochondria in a similar fashion.
Electrical Potential
The electrical potential of the cell membranes in eukaryotic cells stores the light energy in the electrons it captures photoelectrically. Captures light “excites” the electron. Any time an electron is captured by a semiconductor and it becomes a particle only and loses its wave ability.
These facts idea leads us to one conclusion: the electrical potential difference between two sides of a membrane can be harnessed and used to perform cellular work whenever it is needed. Why can energy be harvested in life, anytime it wants it? The photoelectric effect is instantaneous, therefore time is no longer an issue for energy transfer. We cannot observe light’s speed so for living things this is not part of our reality, but we know it is true. The speed of light in a tissue is the rate-limiting factor for a cell. What else is key to this understanding?
You begin to see why all eukaryotic membranes are loaded with DHA. They contain pi electron clouds that are waiting to be excited by incident light from the sun to store this energy for the cells uses later on. This explains why DHA has never been replaced one time in 600 million years of eukaryotic evolution, even though evolution is about change over time. Why is it a constant? It is the only lipid capable of turning sunlight into a DC electric current and a DC electric current back to light. What does it release its stored energy to in a cell? Water. What is its photo-electric adaptor or connector water? Potassium ions which act like a glue to make water molecules act differently than they do in a glass.
K+ is s special when it is married to water and light from the sun hits it. So how does this link to technology?
In the silicon integrated circuits, there is a metal–oxide–semiconductor field-effect transistor. It is a transistor used for amplifying or switching electronic signals. When the gate in this set is leaky, semiconductor engineers fix the problem by adding an insulator to the semiconductor to overcome the energy loss of the leaky gate. This insulator has to have a high dielectric value to work well and stop the leak.
Water
In cells, water makes up 99% of the molecules because it is a small chemical. At birth, by weight humans are 75% water. If they get to their 8 decades their weight is 50-55% if they are healthy. This makes the point that cell water and health are inextricably linked. Water links to sunlight to build a huge battery. That better the battery is the longer and better you live.
Water has a very high dielectric constant at 78. K+ is a metal ion inside the cell filled with redox chemical. This makes it very similar to a semiconductor mentioned above. When you use fluoride or bromides in modern products, this lowers the dielectric constant of water everywhere in the cosmos and in your cells. This is not the only way to destroy the dielectric constant of water.
In FQ toxicity, specifically, it is precisely this molecular action on water means you develop a leaky semiconductor just like the leaky gate mentioned earlier. In human cells, we have two types of semiconductors, positive (P) and negative (N) semiconductor. When someone is “floxed” he or she develop a leaky gate in his or her cells that affect his or her collagen. There are many types of collagen in cells. For example, bone can develop a leaky P (apatite) and/or N semiconductor (collagen) because both collagen and water (the high dielectric insulator) altered by the halogen in the FQ antibiotics. This loss of energy at the gate position of your semiconductors causes huge energy losses. It lowers the exclusion zone in water. This reduces the electrons in water and does not allow it to absorb as much light. Light interacts with water photoelectrically. Photons can only interact with electrons according to quantum electrodynamics.
On short timescales, you can not overcome the electron loss in intracellular water (EZ) because of how halogens reduce an electron density in water chemistry. This is why chronic fatigue is always part of the syndrome. In other words, your cells have lost to the ability get the energy stored in their semiconductors whenever they need it. Without energy, fatigue rules a person’s existence when they have been “floxed”.
Water makes up 99% of molecules in every cell, so it is akin to driving a car constantly with a discharged battery due to a bad alternator. The battery just cannot recharge. In order to overcome the increase in energy loss in tech gear due to gate current leakage in silicon, a high-κ dielectric is used instead of silicon dioxide for the gate insulator, while polysilicon is replaced by metal gates. We can not do this in carbon-based semiconduction in cells. But you need to be aware that blue light exposure at night and non-native EMF day or night exacerbates this problem of electron loss. This is why “floxed patients” need to be very careful with modern gadgets. I have a sense this is why patients who are anesthetized by fluoridated anesthetics also have trouble with recover and often report worsening of their neuro-degeneration. This is one reason why isoflurane is no longer being widely used in medicine during surgery. In surgery, we have an environment that creates the perfect storm for mitochondria and the exclusion zone of water, namely, the use of fluoridated drugs in a strong blue-lit and nnEMF environment.
When you use these drugs, we need to avoid blue light and non-native EMF like the plague because of both un-zip collagen and break down the water-MINOS layer around the mitochondria even more. This further lowers the dielectric constant of water in a cell. This affects how all voltage-gated channels act within the cell. No drug can fix this type of mechanism because it alters the electrostatics binding affinity inside the cell. Only slow replacement of proteins and cell water with the addition of natural sunlight to the system can slowly help aid in a recovery. Sunlight can affect the viscosity of water inside a cell to alter the ATPase function (2).
This situation can also cause you to lose water inside the cell via dehydration. When we are born humans are 75% water but each decade we lose our % of water inside a cell. This lowers our tolerance for fluoridated chemicals as we age. Anytime you lose water you lose the ability to add light back to the system to create the battery that a mitochondrion uses to drive the ATPase inside a cell. This really limits the light energy that water can carry in your cells. In case you don’t know, Dr. Gerald Pollack has shown definitively that water is a repository for all electromagnetic radiations. Electromagnetic radiations = light; all light is not the same. Sunlight always is better than artificial light when it comes to biology. The reason for this unusual finding is that water inside a cell adjacent to our proteins likes some frequencies better than others. Our proteins are all fluorophores or chromophores. This implies they like purple (UV) and red IR light. Water specifically has a molecular love affair with UV and IR light and hates microwaves and blue light frequencies. Loss of electrons or water allows collagen to un-zip in all places of your cytoarchitecture. This can lead to tendinopathy and tendon rupture, chronic fatigue, neuropathy, and exacerbation of CNS and neuroimmune function because your mitochondria are losing electrons, dehydrating, using more calcium and magnesium, and the respiratory proteins stretch-out.
This slows electron chain transport. Any time ECT is slowed, diseases manifest because we need the excited electrons to store their light energy in our cells for use when we need it. This is called increase % heteroplasmy. If this happens sequentially over a few weeks of taking a prescription while your inside watching TV or on a laptop, your cellular architecture can be damaged badly in tissues where the halogens concentrate in to disrupt mitochondria and cell water. The reason chronic fatigue stays around is that no one realizes how the environment worsens and protracts the condition of water inside of cells. One of the best ways to limit the effect is getting AM light with UVA and IRA light to lower heteroplasmy rates in your mitochondria. In fact, IR-A light and cold thermogenesis can really help those who got “floxed” because it increases ATP.
This does not allow you to make as much energy from the water around the MINOS in mitochondria. You need to carefully read OSF #6 blog to get the full effects of what can happen. This is why being “floxed” can have many symptoms that seem disjointed to the clinicians who see these patients. Water chemistry is a big problem in “floxed” patients. To make repairs to the ecosystem in your cells, you need to replace the bad collagen, and dramatically improve the dielectric constant of intracellular water using the correct light frequencies. Water has a naturally high dielectric constant (78). In “floxed” people it drops like a lead weight.
In this case, when water can not carry the right amount of energy cells cannot signal properly to function. Think of a plant in your mind to make this point. If it has little water and not much sun will it grow and live well? No.
Realize water inside a cell, and the level of potassium ions (K+) in a cell are linked. Energy is tied to K+ and K+ are coupled to ATP levels. ATP converts mechanical energy to chemical energy. Light is what activates ATP. Red light specifically has been shown to increase ATP due to its effects on cytochrome 3 because it shrinks the geometry of the respiratory proteins. K+ ions also link to water molecules and in turn to ATP molecules stochastically. Stochastically = statistically. Here we are back to Brownian motion, Maxwell, and Einstein’s papers mentioned earlier. What is the circle of life?
For Physics Geeks
For every 0.3 mEq below 3.8 mEq that potassium is on a standard blood lab draw, means there is 100 mEq deficit of potassium INSIDE a cell. This deficit causes a mitochondria to consume more calcium and it swells. This slows ECT because it increases the distance of the respiratory proteins. The atomic size is linked to the redox potential in a cell because it is linked to the electrostatic attraction in a cell. This is huge for potassium ions (K+) ability in “gluing of water”. Potassium ions are able to glue water because the ion’s atomic radius allows it to polarize in sunlight. When somebody is “floxed”, the polarization of the ion becomes smaller than cell water. This causes a huge electric problem in the cell because polarization energy of K+ is subtracted from Coulomb energy. Normally K+ is more polarizable than water, so polarization is added to the Coulomb energy in a cell. When fluoride or bromide are added to a cell for any reason, dielectric collapse occurs. This is precisely how the dielectric constant in water is destroyed in “floxed patients”.
In the normal state of affairs when a cell is working and the patient is not “floxed”, this allows potassium to function as the optimal “photo-electrical adapter” to transfer energy throughout the cell coherently. It is also massively important in “floxed patients” because intracellular dehydration from EMF completely ruins this relationship and this is why they find it so hard to get better fast.
ATP is designed to unfold proteins fully to open their carbonyl and imino side chain groups on all amino acids to intracellular water. All proteins only function in a cell when they are surrounded by a hydration shell. This action allows binding and polarization to separate water into subatomic particles that are positively and negatively charged. This action is called building or expanding the exclusion zone (EZ) of water. Dr. Gerald Pollack’s experiments showed these effects. Dr. Gilbert Ling proved this by experiment that each molecule of ATP in a cell controls 8,800 water molecule binding sites and 20 potassium ions to allow water to become structured inside every cell of your body (Pollack and Ling referenced below).
Back Around to You, the Floxed
How does all this link back to life and you? The first step in photosynthesis and in mitochondrial oxidation/phosphorylation of electrons is to charge separate water. One wonders where a person or animal or plant begins and ends when you realize this linkage. The reality is that life is really a continuum of physics built upon the sliding scale of geometry on our respiratory proteins, to create amazing diversity. Ling was the first to realize K+ ions were linked water chemistry and eventually to the ATPase. This is the sliding scale a “floxed patient” needs to pay attention too. When the ATPase slows proteins remain unfolded and water cannot bind to them to transfer energy throughout the cell. So when you have altered poor K+ ion and you’re dehydrated by our modern world, your cell’s interior becomes pseudo-hypoxic and NAD+ levels drop. This cause mitochondria to swell and calcium homeostasis is lost. Cells begin to leak electrons and light in the form of ELF-UV light. This causes a redox shift of the mitochondria cytochromes and increases the distance between the respiratory proteins. In other words, your mitochondria down shift electron tunneling speeds, by slowing their ECT flow, to protect itself from short-circuiting. They do this because of the lack of electrons and water. This is why ketosis is a partial fix in “floxed” patients. This becomes energy costly to a cell. Every stressed cell releases ELF-UV light. When this happens chronically in many tissues sequentially because of how drugs are prescribed your cells that need energy are starving for it.
This is what chronic fatigue is, fundamentally. It is a loss of energy transfers in a cell and associated with a light loss in the UV range and IR range. When light is lost, matter in a cell cannot be made properly. If substrates for biochemistry cannot be made cell function grinds to a halt. Cortisol is one of the hormones we need to work with collagen in our body to do many things. One of them is to unzip in the AM to wake us up. This is why many “floxed” people have sleep problems. AM sunlight is designed to make re-zip collagen in cells. It also helps make matter in cells.
Light
Light builds hormones, like cortisol, by first building dopamine in our retina using aromatic amino acids that absorb UV light from the sun. People who are floxed and too tired to go outside get more ill. Staying indoors under blue light and using nnEMF compounds the illness. We see the same thing in Lyme disease and hypothyroidism. AM sunlight is used to power up electrons. What happens if no electrons are present to excite? You get tired and ECT slows. In our body AM sunlight is designed to power up electrons and they get assigned a spin in mitochondria to make free radicals. This process is also ruined in floxed patients. So sunlight acts as the currency for the compound pharmacy in your pituitary every day to make things we need from light. This process is usually broken in floxed patients. The electromagnetic spectrum has 73 octaves. Visible light only makes up one octave of the spectrum of light. If you understand factorial math, that means within our one octave, our retinal cells are capable of controlling many biochemicals substrates. Our one octave of visible light in the electromagnetic spectrum can handle 8,683,317,618,811,886,495,518,194,401,280,000,000 different frequencies. Each frequency of light can control one chemical. It is well known that when chemical bonds are excited, they will vibrate at characteristic frequencies. Any two or more bonds which have the same intrinsic frequency of vibration can resonate with another. This idea is how a tuning fork that is vibrating can make another non-vibrating tuning fork vibrate through the air to resonate.
What most doctors and few researchers seem to know is that the energy of vibration can be transferred infinite distances theoretically, if the energy within the chemicals or tuning forks is radiated at the speed of light! Above I showed you that Becker showed the photoelectric effect is active in collagen. That means the chemical vibrations in your floxed cells are slowed because the water around them slows the speed of light in your cells. What are the key fixes? New water, and more sunlight, fasting, and ketosis. This must be the order of repair and it the reason is simple. You have to shrink the geometry of your respiratory proteins down before you can add backlight energy or you will fry your mitochondria with too many electrons too early. In my experience, this takes 18-36 months and the main variable is how much technology a floxed patient is addicted too and how little sunlight they get daily.
Let me say this again; there are 8,683,317,618,811,886,495,518,194,401,280,000,000 different frequencies of light in visible light spectrum from 250nm-780nm of the sun that comes to Earth daily. Each frequency of light has the ability to control one chemical by resonant energy transfer mentioned above. This is a staggering level of power and control that sunlight has on a cell. A floxed person must realize this at once and drop all pills and supplements. Sunlight is your most powerful Rx in this condition. So when you open up any biochemistry book and realize that biochemistry only uses 100,000 chemical substrate in all biochemical reactions we know about in our cells, you realize light is a critical factor for energy management in a cell. When you factor in that the photoelectric effect acts instantaneously on our skin, with no time delay, then you begin to see how 100,000 biochemical reactions can occur per second using light frequencies from the visible spectrum easily. It also makes sense how these light frequencies match the frequencies of the vibrations of chemicals to offer this level of organization.
All sunlight is unpolarized, and unpolarized sunlight interacts with K+ ions inside of your cells to turn water into a “glued sea” inside our cells. that sea controls the speed of light in our cells using something called Fermat’s law. This allows cell water to acts like a colloid plasma would in space. When you are “floxed” you lose the ability to make this glued sea of energy, and as a result, the speed of light in your tissues lowers. when it lowers your tuning fork proteins inside you can no longer connect well to the incoming light fast enough. The result is you feel terrible. Your cortisol is usually ridiculously low and your sleep is destroyed.
It takes time to recover because of the damage was done. Recovery is usually based upon how much “cellular real estate” of the cytoarchitecture is involved. It involves ubiquitination pathways that mark damaged proteins for removal and they only work during autophagy. So intermittent fasting, sleep, and water-based exercises to increase external pressure, and cold thermogenesis are some of the best ways to help someone with this condition while they are increasing RO water and iodine intake via seafood. Supplemental iodine is usually not effective. Once your mitochondria begin to heal and lower their heteroplasmy percentage, then ketosis can be introduced to increase ECT speeds. Using ketosis when your respiratory proteins are expanded and swollen will cause you to develop a more chronic lifelong condition. Removal of the halogens will happen naturally when you replace the collagen by autolysis and autophagy. You need to read my blog and my book, the Epi-Paleo Rx. If you follow these ideas consistently 5-7 days per week for at least 2-3 yrs, you will begin to make a dent because you will recover your heteroplasmy ratio in cells. Heteroplasmy = smaller mitochondria = smaller geometries on the respiratory proteins.
You need water and DHA to replace the lost electrons so you can capture more photon power in light to heal your mitochondria. Heteroplasmy repair is really a sunlight story. To absorb it best you need water replacement and you should be grounded to the Earth. When you add back DHA to most of the cell membranes in your body to become energy efficient once again to make the hormones like cortisol and biogenic amines like dopamine and melatonin.
When you are “floxed” you need a lot of electrons to get better. You also need a sizable dose of natural sunlight. You should avoid blue light and technology too! There is no supplements or therapies that will be your magic bullet, I am sorry to say. It is a terrible disease because of what it does and how healthcare treats patients deepens the insult because few people understand the biophysics of the condition. This really frustrates patients with the condition and leads to serious anxiety and depression. Your body has to recover from the halogen insult, worsens by technology use, and you need to give it the natural substrates to do the job to lower heteroplasmy rates. The use of red light, avoidance of blue light at night, getting daily sunlight on your skin, your retina, and massage/reflexology can be helpful if it is part of your budget.
The big elephant in the room is your use of blue light devices that also use non-native EMF exposure because it destroys intracellular water which is the critical part of recovery; the disease becomes worse because of the addiction to silicon-based technology cause electron leak in our cells. The leakier we are, the longer the recovery will take because the more bad EMF, the more dehydrated you become, subsequently, the worse autophagy operates because of altered calcium homeostasis; this is the process you need to consider to activate to get better.
More information about Dr. Kruse
Article cites:
The Fourth Phase of Water, Gerald Pollack
Life in the cell and below the cell level, Gilbert Ling. (May take a while to load)
Fascinating! I drank almost a gallon of water a day when floxed. Cuz I had and was passing hella kidney stones too. I refused any pharma cuz look what 10 days of Cipro did to me 6 months later! I could NOT eat (still struggle with eating) cuz it hurt too badly. Lived on spoonfuls of cold sweetened condensed milk. And tho I was disabled for a year, and tho I still struggle with the cycles of mental n physical aftermath: I call myself a lucky floxie. I didn’t pop a tendon tho each tendon n LIGAMENT in my body screamed in burning pain. I survived. I went back to work. This article tellsme my instincts were spot on! And now I also understand why rainy days mess me up. Thank you.
This post is AT BEST just an advert for the supposed doctor and his book (according to linkedin, he has a Bachelor’s degree in psychology, then trained in dentistry, then did a three-year medical conversion course, since when he has worked primarily as CEO of “Optimized Life”).
If I were a peer reviewer, some of the comments I’d like to make are as follows:
The reasoning is rife with logical jumps and poorly understood /inaccurate /misapplied chemistry. It overloads the reader with ‘clever sounding’ words and phrases but makes little sense whatsoever. The opening paragraph claims it to have been published, leading the reader to assume scientific validity, but in actual fact it links only to an informal answer on the author’s LinkedIn page – this is NOT a valid form of publication in this regard. Furthermore, the post is wildly lacking in references to back up the immense breadth of science it purports to cover. To close, the English in which it is written is so poor as to obfuscate the meaning of a significant portion of sentences. Even allowing some creative licence to the reader in mentally editing the sentences, the majority still read as false or irrelevant.
I confess I lack medical education, and that my biology, biochemistry and pharmacy is very flox-specific, gleaned from my reading of the literature. But I do have a quality, broad MSci in Chemistry (and a PhD, although it is less relevant), broad enough to reach into much of the physics ostensibly covered herein, and where I do have relevant education I find myself cocking my head and frowning as I try and make sense of the claims and reasoning presented. To claim that the concepts are complex for the average reader… I work in academia and not a single paragraph in this post rang coherently true to me.
And why do I object so fiercely to this? Because people int he Floxie community have approached me to ask for my opinion on this post, it having provoked them to fear and anxiety about things they rather cannot avoid. Having read it, I could only go so far as to tell them to forget it and that almost every claim made herein that I have relevant education on is either irrelevant, or spurious-at-best where not entirely false. It is my firm opinion that, if this post is to remain, the author should provide a thoroughly cited version, edited by a native English speaking co-author, at a level comprehensible to a graduate student, or with the opening caveat that it is deemed strongly controversial.
to DrHungrytheChemist: Helllo…everything provokes floxies to fear and anxiety. Especially newbies. For some, it is alternative health practitioners, others it is traditional allopathic physicians. Like David said, you can’t make everyone happy. Just be thankful that David still has his blog and discusses a very difficult subject. Do I agree with everything he says, no. Hell I don’t agree with most people 100% of the time, but I sure as hell don’t go around telling them to take down posts because I don’t agree with them. Nor do I hide behind my credentials as an auto mechanic, which I admit is less relevant also. You, my friend are a pompous ass.
, I approved this comment to show my average reader, for lack of a better word, defecation, that you have to put up with when you run a blog such as this. They messages, emails, posts are often from inflated intellectual types, representing either medicine, alternative or allopathic, legal, science, or somewhere in between. Also on a side note, this is why I have certain pages available to registered users only, because of sensitive people who have thresholds that are impossible to predict. The moral: you can’t make everyone happy, so don’t even try.
First, you hypothesize that “If I were a peer reviewer,” well my friend (termed used loosely), although I occasionally use peer reviewed papers, this site does not represent an academic institution or empirical science (if there is such as thing). Nor is my site peer reviewed.
Second, the article, which was written by Jack Kruse (source is cited), is for information only. Take want you want from it, or leave it. It is as simple as that. Even I don’t agree with everything in it myself. However, I present it in its entirety and assume my readers are adults and can decide for themselves whether they want to look further into claims or call it BS and move on.
Third, and to reiterate, I do not hold people’s hands, I do assume they are adults, and usually don’t censor much of my material. My blog is not a democracy where you get to choose what I post or not post (it is more of small country where I am more of a benevolent dictator). On the contrary, it is written by a chronically floxed sick man just trying to figure this floxing thing out. And I am actually doing a pretty good job considering the academic institutions that I have worked with, academic papers I have contributed to, etc…(see I can self-aggrandize too, oops!). I do my best, and yes at times my grammar, spelling, and political correctness suffer. Although normally I would file 13 most narcissistic ego driven critic tantrum posts, such as yours, I post it as a learning experience for others to see, and because you tacitly inserted your qualifications as a professional.
Fourth, I undoubtedly have been in the FQ community for a long time and this is not my first rodeo. You openly throw out your education and even throw out the fact that you consult people in the floxie community but don’t have the cojones (using nice language) to give your name, hiding behind your credentialed mask. You see, over the years, I have gotten contacts, and there have been many, from supposed doctor/expert types whose claims run the gamut from, floxing is ridiculous given the absolute empirical safety of FQs, to the fact that FQAD is a psychosomatic illness and needs to be relegated as such. They cite their credentials and their empirical academic papers (many have much better credentials than you by the way). So your critique, although humorous, holds little weight, with exception of educating us on how not to go on to someone’s personal blog and tell them how to run the show, at the same time sounding pompous and arrogant. I am not a doctor and never claim to be one.
Bottom line, I present all types of data about floxing from all modalities.
Also, if you have a problem personally with Dr. Jack Kruse, his grammar, education and or even want to criticize his hair cut, please by all means take it up directly with him.
P.S. One last thing, I will post a trigger warning at the top of this article, like I do on some others. In this case it will be to serve as a warning to sensitive educational types, like yourself, that they may find the quasi pseudo-science content disturbing. Again, thank you for giving us this opportunity to learn.
My comment was aimed to show a lay reader who reads it without this “flavour of equal posting of ideas” and presumes that it must make factual sense that someone out there disagrees. It was not designed as an attack on Admin, in and of itself, recognising that they did not write it themselves. Rather, the re-posted content and implication that it is valid by posting it with the caveat that the ideas are complex [and therefore factual whether or not someone can wrap their head around them]. It is not that the ideas are complex, it is that they are rife with falsities that undermine the argument throughout but take high-level knowledge to recognise (primary example, metabolite analysis of cipro does not show C-F bond cleavage, said cleavage being exceedingly rare in nature, thus the entire fluoride argument is unfounded).
I appreciate that you are sharing ideas and notions you find around the place, surely that is a very good approach to generating discussion and expanding knowledge. But my point lies in that, as your “little country”, do you not have a duty of care to warn people that a post may be riddled with falsities? While this is no democracy, neither really is scientific fact, and while there are adults in this world, there are also plenty in their early 20’s (and indeed beyond) who have yet to learnt that you can’t trust everything claimed by a clever-sounding argument. When someone is busily crippled by the terror of an early floxing (as another comment notes of the community, albeit to a different end), surely we who are further along and now more level-headed should indeed behave in sympathetic care to them?
You’re right, I did consciously elect to use my internet pseudonym. The reasoning was threefold. Firstly, given my activity elsewhere, it leaves me more accountable to the floxie community which I entered under this psuedonym, weaving a more full thread of that person as I go. Secondly, I’m not foolish enough to suppose that putting my my true identity to something like this in the public domain doesn’t carry risks. Finally, I am an early career researcher, still building my reputation, and I indeed wanted to keep such discussion separate from my career identity. Yes, that does reflect my confidence in how socially acceptable my posting may be received (clearly I failed to adequately convey what it was and said by whom I was objecting about and critiquing as I went through, while equally managing it in such a fashion as for it to be taken personally and not as an attack on the content, and that has caused quite the stir).
To mock my being disturbed by false claims is to mock truth and education. You only make yourself look as petulant and sensitive as you accuse me of being. You undermine your own character by the present comment/trigger-warning combo.
Thank you for your eloquent response.
Again, your original critique hit the light of day because your esteemed credentials, and that you acted as a science intermediary for some concerned floxies (newbies I assume)(also I realize that it was mostly directed at Dr. Kruse, but there were peripheral issues that encompassed a broader spectrum).
First, me, petulant? Yes, quite possibly. My wife would definitely call me petulant at times. But before I give a feeble attempt at reasoning for my ‘petulance,’ let me take a step back and fill in some back-story. I believe that your viewpoint, or insertion, on this matter is one from a very myopic perspective in a much broader timeline, while I, myself, come to this with the benefit of thirteen years of dubious experience. I am afraid, you fell into one of the classic blunders – the most famous of which is (quote Princess Bride) “never get involved in a land war in Asia” – but only slightly less well-known is this, never get involved in the battle for empirical science in the FQ realm.
I won’t bore you with my academic background as most readers would probably accuse me of too much self-aggrandizement, however, one thing I have found, over the years traveling through academia, and especially driven home in the FQ realm, is that the claimed empirical nature of science does not exist as most see it or want to see it.
Whether we are talking how cell line misidentification contaminates the scientific literature or how Richard Smith, former editor of the BMJ stated most scientific studies are wrong, or how John Ioannidis, professor of medicine at Stanford says that most medical published research findings are false, science has a problem with credibility, especially in the FQ realm. These types of errors definitely permeate the FQ realm on the academic end. Since you are approaching this discussion from a more academic viewpoint, I won’t even begin to critique other modality aspects.
Let’s say academic researcher ‘A’ contacts me, with a scathing critique of my view of how the FQ’s interfere with mtDNA Topoisomerase Top2β in brain tissue. To bolster his case, he cites peer reviewed empirical academic science as the source of his rebuttal. He claims that my view goes against proven science fact.
Then, on the same topic, academic researcher ‘B’ contacts me and says that my view of mtDNA Topoisomerase Top2β in brain tissue, is absolutely correct, also citing peer reviewed empirical academic science as a source. (Seriously, this has happened to me on more than one occasion, and under different medical modalities).
Who is right? Both claim the same ‘right’ of having scientific fact. Both researchers A & B will rail against one another claiming superiority of the factual arguments, citing peer reviewed data that they claim is empirical.
In my little world, this little war occurs regularly between several factions, allopathic, naturopathic, homeopathic, all claiming some sort of empirical knowledge, or at the very least ‘insider’ knowledge of the subject matter. And then there is the annoying first-year medical student who will write in to lecture me on my poor understanding of the term ‘chemotherapeutic’ one of my most ardent critics, who just can’t wrap his head around the fact that FQ’s are anti-tumor medication (Sorry I, went a bit far afield).
Now let’s take Jack Kruse’s explanation of Cipro toxicity. I know your argument is that Kruse violates basic tenets of science, mostly from a chemistry viewpoint. Nevertheless, do I find some kernels of truth mixed in his supposed ‘pseudo-science’? Yes. Do I understand everything that he has written? No. I am somewhat like that little dog with it’s head cocked, hoping that by moving my head into the right position I will get a different perspective? Yes. Nevertheless, I do know that some my readers have claimed to have been helped by his ideas, so I throw them out there like abstract art, letting it hit the wall and slowly run down, thereby letting the viewers extrapolate what they will.
Me personally, I am kind of like that abstract art, eclectic, and literally all over the place in the FQ realm. I used to be rigidly empirically minded having worked with three academic institutions, contributed to published papers in the BMJ, European Journal of Medicine, the Journal of Community and Supportive Oncology, and contributed data to many more papers and case studies. And yet, I even have written articles for *cringe* Dr. Mercola, who some consider the pinnacle of pseudo Medicinal Quackery. Anyway, the people I seriously work with know what my viewpoints are and are good with it. Others, well they can pound sand.
You might be asking yourself right about now, how do I determine truth when all these voices are clamoring for factual superiority and so much is unknown about FQ’s? In the FQ realm I use anecdotal information that I have built over the last thirteen years as the final arbiter. It is true, and my friends will tell you, I am hard on both alternative and allopathic (traditional) views of medicine, and to a lesser extent science, because I have seen hucksters on both sides. Personally, my greatest disdain is for many, not all, chiropractors who practice outside their realm (genetics, etc…) and victimize people monetarily. Some of these practitioners truly believe that they are ‘doing right’ and sometimes I cut them a break. If I know or suspect they are legitimate scams I treat them as such and most of their correspondences with me won’t see the light of day.
One final point thought, and my reason for bringing up the Vizzini in the first paragraph, I garnered from your original post that you did not spend much time perusing my blog. For if you did, you would find that this site is dedicated to Chronically Floxed Folks. Although I do help newbies on occasion, my passion is to figure out what happens to, and work with, chronically floxed folks or those suffering from FQAD, which I myself also am a sufferer. Chronically floxed folks have even less real estate for help on the Internet than newbies to the FQ realm. Most of my audience has a above average understanding of chronic floxing; they understand the desperate struggle for recognition in the medical realm and I find most are above average on their basic concepts of metabolomics, epigenetics, mitochondrial metabolism, and so on (mainly due to survival reasons).
Newbies, on the other hand, are all over the place. Like one of the other commenters said, they are fearful of everything. Some have demanded censorship, such as removal of ideas or concepts that they find fearful and for that very reason, some of my pages are registered users only, or heavily caveatted. I make it clear in many places on this site that I cater to a certain readership, that being the chronically floxed. Newbies generally migrate to sites like Floxie Hope that paints a more sanitized picture of floxing. Unfortunately, in my opinion, it also paints the wrong picture for politicians, policy makers, and worse yet medical professionals who walk away seeing Floxing as a curable, recoverable syndrome. It makes it easier to turn a blind eye or claim plausible deniability. Yes it is true, I do paint a more ugly, but truthful less sanitized picture. Here my anecdotal statistics speak a much a different picture than what is presented on other parts of the Internet as I get many of the supposedly ‘cured’ cases returning weeks, months or years later.
Am I without compassion for the newbies? No, not at all. Having been there, I understand their plight, but my job is not to sanitize or make the Internet a safer place for them. I don’t have the time, patience, nor health reserve to do so.
I will conclude because I have expended too much time, energy, and my hypocrisy goes only so far, but my hope is that others will learn from this exchange. If I have come across as unkind, I apologize, but as you can see there are deep waters.
I have limited commenting on this article to just the article, except for Dr Hungry as to keep this comment stream from degrading into a defecation storm.
P.S. Since you were good enough to respond I did change that trigger warning at the top to a less petulant display. The trigger warning will still stand so that other sensitive readers remain forewarned.
David, the old Abraham Lincoln quote that is based off of Proverbs comes to mind: “Better to remain silent and be thought a fool than to speak and to remove all doubt.” Dr Hungry, needs to consider the audience before posting such drivel. I for one have been around a while, and am not impressed.
I disagree and do not think that that article should removed, Why? because it upsets someone! Oh get a life! It doesn’t take long to Google Dr. Kruse to find out what you need to know. Besides, even though I don’t completely understand a lot of what he wrote, I still got a few good points out of it. I, for one, have been helped by sunlight therapy and I could never explain why. Something more than SAD. Maybe Dr. Kruse is onto something. .
In the interest of full disclosure I am an MD, Phd Pediatric ophthalmologist. I occasionally read David’s blog and converse with him every once in a while on the subject of FQAD. I stumbled upon his blog years ago when searching for patient experiences with FQ’s. I have been very supportive of his work, especially with the academic institutions and his role advocating to the FDA. As David can attest, I have been politely critical of him in the past on a few matters of medical science, but overall his grasp of scientific subjects is above average. Although David doesn’t tout his education, I believe he is more credentialed than our esteemed critic, given what little we know about him/her. I do not feel compelled to defend David since he can and did an admirable job of responding. My main point is that I don’t agree with almost everything thing that Jack Kruse says in this article, or in general for that fact. I feel that Kruse’s science is frankly bizarre and disjointed. Despite this, I consider the context in which it is presented. Going to a blog that presents all sides of a subject and criticizing the blogger for presenting a certain controversial viewpoint is tantamount to going to a Volkswagen dealership and getting upset that they don’t sell Hyundai’s. I find this style of critique about as faux and self-serving as I do much of Kruse’s material.
Thank you, as always, for your insightful responses Doctor G.
I appreciate your comment. Clearly I need to articulate the crux of my objections better, and perhaps I need to moderate my expectations of internet blogging etiquette. Still, in a world where misinformation have given us Trump, Brexit, climate-change denial and anti-vaxxers, I find myself very easily triggered by the sharing of false claims under titles that claim a degree of reverence (not ignorant to the ironies of my saying that).
I understand why you allowed his comment through but in all reality I doubt this critic has even looked over the rest of the site to get a flavor for what it is really like. I for one like the way you present more than one viewpoint on a subject.
In my two replies above, I have now given answers that answer around the crux of your comment (fyi).
DrHungrytheChemist needs to get a job with Facebook. They are always looking for good subjective censors.
The existentialist philosopher Criss Jami wrote, “A solid answer to everything is not necessary. Blurry concepts influence one to focus, but postulated clarity influences arrogance.”
Carla, Thanks that is a good quote. I will have to use it in the future.
I can’t stand these Hit and Run Antifa type critics. DrHungrytheChemist, for all us stupid folk, please enlighten us on what causes FQ Toxicity? I’ll be waiting your learned response, but I won’t hold my breath.
I’m not claiming here to have the answers, instead I’m trying to cast doubt on some false claims. I shall not insult this board by attempting to cobble together the level of understanding I’ve gleaned in the context your question. I obviously don’t have the answers and what I do positively have on topic is indeed rudimentary and vague, much as is the current understanding.