I am starting to get good reports from people suffering from FQAD about Fatty15.Fatty15

What is Fatty 15 you ask? 

Fatty15 is technically pentadecanoic acid, commonly referred to as C15 or Fatty15. C15:0 is the first essential fatty acid to be discovered since the omegas—over 90 years ago. It is an odd-chain saturated fatty acid that has been garnering attention in the health and wellness communities for its potential benefits, particularly in relation to mitochondrial health. Mitochondria, the powerhouses of cells, play a crucial role in energy production and overall cellular health and are often damaged in various ways from Fluoroquinolones leading to a host of problems. From all preliminary indications Fatty15 appears to have a significant positive impact on mitochondria.

For my readers who like to geek out on the science, C15:0 is a sturdy, odd-chain, saturated fatty acid that integrates itself into cell membranes to fortify and strengthen them, giving them better protection against oxidative stress and cellular degradation than omega-3 fatty acids. Studies show that C15:0 supplementation improved cellular stability by 80% (1).

Mitochondrial dysfunction/disease is a key hallmark of Fluoroquinolone toxicity and in turn that drives, or contributes, to the onset of chronic diseases (FQAD). C15:0 increases mitochondrial function by up to 45%, keeping our cells active and ensuring they’re able to carry out cellular processes as they should. The mitochondria produce ATP, your cell’s energy currency. In studies, C15:0 was able to increase ATP by up to 350%. A pretty impressive feat!

C15:0 Long-Term Benefits  

C15:0 (Fatty15) has been shown in peer-reviewed studies to: 

  • Strengthen cellular membranes, making them more resilient against age-related breakdown. Fatty15 contains pure C15:0, which is a sturdy fatty acid that imbeds into the lipid bilayer of membranes to protect cells against lipid peroxidation. Fatty15 has been shown to improve cellular stability by 80%.
  • Repair mitochondrial function and restore cellular energy. Fatty15 has been shown to improve mitochondrial function by 45%. These benefits result in increased ATP energy production and reduced reactive oxygen species (ROS). 
  • Naturally activates AMPK to support glucose control. Fatty15 activates AMPK, which supports our long-term health and is a core component of the human longevity pathway.
  • Lowers multiple pro-inflammatory cytokines to balance immune responses. Fatty15 lowers key cytokines, including IL-6, MCP-1 and TNF-alpha, which are responsible for aging-related breakdown.
  • Naturally activates PPAR-alpha and delta receptors, which regulate our metabolism and immunity. Additionally, PPAR-alpha activators have been proposed to support brain health, while PPAR-delta activators can be heart protective.

C15:0 is also helpful in assisting with clearing damaged cells. Some people FQAD suffer from an accumulation of damaged cells. C15:0 activates AMPK and inhibits mTOR, which are important mechanisms to slowing cellular senescence and clearing damaged cells. AMPK is also essential in regulatory processes, like glucose uptake (2).

C15:0 (Fatty15) near-term benefits:

  • Near-term roles of PPARs. Many of fatty15’s near-term benefits are due to fatty15’s role as a natural activator of two key receptors, called PPARs (pronounced pee-pars) alpha and delta, that are present throughout our body – including our brain. In addition to these long-term benefits, PPARs help to regulate our mood, stress, sleep patterns, energy, and hunger. 
  • Near-term roles of PDC. Our bodies use C15:0 to naturally make a second molecule, called pentadecanoylcarnitine (what we refer to as PDC). PDC is the second-ever discovered full-acting endocannabinoid and has been shown to:

    • Activate CB1 and CB2 receptors as an endocannabinoid that can help to improve joint comfort, mood, and sleep.
    • Activate 5-HT1A and 5-HT1B receptors to reduce stress.
    • Inhibit histamine H1 and H2 receptors to calm immune responses.

Unfortunately a person can’t get C15:0 by just eating foods. The short of it is that while C15:0 is available in trace levels in food, especially whole fat dairy products, food-based C15:0 is tied up in complex lipids called triacylglycerides, which we cannot absorb.  If you attempt to get large amounts of C15:0 from dairy you would have to consume an outrageous amount of dairy fats that would give you a much higher levels of ‘bad’ even-chain saturated fats (like, C16:0) and the negative effects would greatly outweigh the positives. 

Another positive is that it also appears that for some people who cannot tolerate Omega-3’s, C15:0 seems to well tolerated and C15:0 is dosed in one small capsule per day and delivers the same benefits as Omega 3’s plus much more. 

Side effects: Since C15:0 was discovered as an essential fatty acid in 2020 and introduced to the public in 2021, over 17,000 customers have taken fatty15 with very few side effects. A few minor side effects have been reported in less than 0.1% of customers: constipation, diarrhea or  headache.  Due to confounding factors it cannot be confirmed confirm that these side effects are directly attributable to C15:0 supplementation.  One floxed person reported a minor headache that went away after a few days, and another reported a transient case of nausea. 


Right now, Fatty15 (C15:0) is only available to purchase from the company who discovered it, and that is a the Fatty15 website. They do not sell on Amazon or in retail stores.  Keep in mind that Fatty15 is not a magic cure all.  It is however a substance that shows promise in the ability to heal heal or support injured mitochondria, in addition to providing other benefits.  My opinion is that it might benefit those who are suffering from mitochondrial issues stemming from fluoroquinolone toxicity and I have had reports of improved energy and sleep. 

One drawback is that like many new products, it is expensive, and it needs to be taken for a while to achieve full benefits.  I have secured a 20% discount for those who want to try it by just clicking on the Fatty15 bottle below.  You will then be taken to the website for Fatty15.   As usual, any benefits received for the referral link will be passed-on to other floxed people. 

Fatty 15